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UniProt functional annotation for P13591 | ||
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| UniProt code: P13591. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. |
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| Function: | |
(Microbial infection) Acts as a receptor for rabies virus. {ECO:0000269|PubMed:9696812}. |
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| Function: | |
(Microbial infection) Acts as a receptor for Zika virus. {ECO:0000269|PubMed:32753727}. |
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| Subunit: | |
(Microbial infection) Interacts with rabies virus glycoprotein. {ECO:0000269|PubMed:9696812}. |
| Subunit: | |
(Microbial infection) Interacts with Zika virus envelope protein E. {ECO:0000269|PubMed:32753727}. |
| Subunit: | |
Interacts with MDK. {ECO:0000250|UniProtKB:P13595}. |
| Subcellular location: | |
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. |
| Subcellular location: | |
[Isoform 2]: Cell membrane; Single-pass type I membrane protein. |
| Subcellular location: | |
[Isoform 3]: Cell membrane; Lipid-anchor, GPI- anchor. |
| Subcellular location: | |
[Isoform 4]: Cell membrane {ECO:0000305}; Lipid- anchor, GPI-anchor {ECO:0000305}. |
| Subcellular location: | |
[Isoform 5]: Secreted. |
| Subcellular location: | |
[Isoform 6]: Secreted {ECO:0000305}. |
| Miscellaneous: | |
[Isoform 5]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAD92680.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.