UniProt functional annotation for Q8U094

UniProt code: Q8U094.

Organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
Taxonomy: Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
 
Function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate.
 
Catalytic activity: L-serine + 1-C-(indol-3-yl)glycerol 3- phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H(2)O. {ECO:0000255|HAMAP-Rule:MF_00131}.
Pathway: Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5. {ECO:0000255|HAMAP- Rule:MF_00131}.
Subunit: Tetramer of two alpha and two beta chains. {ECO:0000255|HAMAP-Rule:MF_00131}.
Similarity: Belongs to the TrpA family. {ECO:0000255|HAMAP- Rule:MF_00131}.

Annotations taken from UniProtKB at the EBI.