PDBsum entry 2dly

Transferase

PDB id: 2dly

Contents

Protein chain

121 a.a. *

* Residue conservation analysis

PDB id:

2dly

Name:

Transferase

Title:

Solution structure of the sh2 domain of murine fyn-related kinase

Structure:

Fyn-related kinase. Chain: a. Fragment: sh2 domain. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: frk. Expressed in: cell free synthesis. Other_details: cell free protein synthesis

NMR struc:

20 models

Authors:

H.Endo,F.Hayashi,M.Yoshida,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

H.Endo et al. Solution structure of the sh2 domain of murine fyn-Related kinase. To be published, .

Date:

20-Apr-06 Release date: 20-Oct-06

Protein chain

Q922K9  (FRK_MOUSE) -  Tyrosine-protein kinase FRK from Mus musculus

Seq: 512 a.a.

Struc: 121 a.a.*

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site