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UniProt functional annotation for P07862 | ||
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| UniProt code: P07862. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Cell wall formation. |
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| Catalytic activity: | |
Reaction=ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate; Xref=Rhea:RHEA:11224, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57416, ChEBI:CHEBI:57822, ChEBI:CHEBI:456216; EC=6.3.2.4; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 magnesium or manganese ions per subunit. {ECO:0000250}; |
| Pathway: | |
Cell wall biogenesis; peptidoglycan biosynthesis. |
| Subunit: | |
Monomer. |
| Subcellular location: | |
Cytoplasm. |
| Similarity: | |
Belongs to the D-alanine--D-alanine ligase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.