UniProt functional annotation for P43627

UniProt code: P43627.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. {ECO:0000269|PubMed:10097129}.
 
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Similarity: Belongs to the immunoglobulin superfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.