PDBsum entry 2dle

Hydrolase

PDB id: 2dle

Contents

Protein chain

104 a.a. *

* Residue conservation analysis

PDB id:

2dle

Name:

Hydrolase

Title:

Solution structure of the fourth fn3 domain of human receptor-type tyrosine-protein phosphatase eta

Structure:

Receptor-type tyrosine-protein phosphatase eta. Chain: a. Fragment: fn3. Synonym: protein-tyrosine phosphatase eta, r-ptp-eta, hptp eta, protein-tyrosine phosphatase receptor type j, density-enhanced phosphatase 1, dep-1, cd148 antigen. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprj, dep1. Expressed in: cell free synthesis. Other_details: cell free protein synthesis

NMR struc:

20 models

Authors:

K.Izumi,M.Yoshida,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

K.Izumi et al. Solution structure of the fourth fn3 domain of human receptor-Type tyrosine-Protein phosphatase eta. To be published, .

Date:

18-Apr-06 Release date: 18-Oct-06

Protein chain

Q12913  (PTPRJ_HUMAN) -  Receptor-type tyrosine-protein phosphatase eta from Homo sapiens

Seq: 1337 a.a.

Struc: 104 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site