PDBsum entry 2dju

Signaling protein

PDB id: 2dju

Contents

Protein chain

106 a.a. *

* Residue conservation analysis

PDB id:

2dju

Name:

Signaling protein

Title:

Solution structures of the fn3 domain of human receptor-type tyrosine- protein phosphatase f

Structure:

Receptor-type tyrosine-protein phosphatase f. Chain: a. Fragment: fibronectin type iii domain. Synonym: lar protein, leukocyte antigen related. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

M.Sato,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

M.Sato et al. Solution structures of the fn3 domain of human receptor-Type tyrosine-Protein phosphatase f. To be published, .

Date:

05-Apr-06 Release date: 05-Oct-06

Protein chain

P10586  (PTPRF_HUMAN) -  Receptor-type tyrosine-protein phosphatase F from Homo sapiens

Seq: 1907 a.a.

Struc: 106 a.a.*

* PDB and UniProt seqs differ at 10 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site