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UniProt functional annotation for Q9QZC7 | ||
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| UniProt code: Q9QZC7. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Involved in retrograde transport of recycling endosomes. {ECO:0000250}. |
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| Subcellular location: | |
Recycling endosome membrane {ECO:0000250}; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR. {ECO:0000250}. |
| Tissue specificity: | |
Highly expressed in brain, retina, heart and kidney. Detected at lower levels in lung, muscle and nerve. {ECO:0000269|PubMed:10200314}. |
| Developmental stage: | |
Highly expressed at birth and up to day 3; expressed at lower levels in embryo and adult. |
| Domain: | |
The PH domain specifically binds phosphatidylserine, which is enriched in recycling endosome membranes, it doesn't recognize PIPs. {ECO:0000250}. |
Annotations taken from UniProtKB at the EBI.