UniProt functional annotation for Q9C5H4



	UniProt functional annotation for Q9C5H4

UniProt code: Q9C5H4.

Organism: Arabidopsis thaliana (Mouse-ear cress).

Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.

Function: Mediates clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network (TGN). Promotes plant growth. {ECO:0000269|PubMed:23771894}.

Subunit: Binds to clathrin heavy chain. {ECO:0000269|PubMed:23771894}.

Subcellular location: Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:23771894}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:23771894}. Note=Colocalizes with clathrin at the trans-Golgi network (TGN). {ECO:0000269|PubMed:23771894}.

Tissue specificity: Expressed in inflorescence stems, stigmas, roots, roots meristems, embryos, and floral and leaf vasculatures, but absent from the floral abscission zone. {ECO:0000269|PubMed:23771894}.

Developmental stage: Strongly expressed in developing and mature embryos. {ECO:0000269|PubMed:23771894}.

Disruption phenotype: Abnormal vacuolar trafficking of soluble cargo proteins, and premature termination of the shoot apical meristem and of floral meristems. Plant missing both AGD5 and MTV1 are severely dwarfed, develop short siliques, exhibit abscission defect, and have altered subcellular distribution of clathrin-coated vesicle (CCV) cargo exported from the trans-Golgi network (TGN). {ECO:0000269|PubMed:23771894}.

Sequence caution: Sequence=AAB63649.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB01267.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.


Organism:		Arabidopsis thaliana (Mouse-ear cress).
Taxonomy:		Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.



Function:		Mediates clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network (TGN). Promotes plant growth. {ECO:0000269\|PubMed:23771894}.


Subunit:		Binds to clathrin heavy chain. {ECO:0000269\|PubMed:23771894}.
Subcellular location:		Golgi apparatus, trans-Golgi network {ECO:0000269\|PubMed:23771894}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269\|PubMed:23771894}. Note=Colocalizes with clathrin at the trans-Golgi network (TGN). {ECO:0000269\|PubMed:23771894}.
Tissue specificity:		Expressed in inflorescence stems, stigmas, roots, roots meristems, embryos, and floral and leaf vasculatures, but absent from the floral abscission zone. {ECO:0000269\|PubMed:23771894}.
Developmental stage:		Strongly expressed in developing and mature embryos. {ECO:0000269\|PubMed:23771894}.
Disruption phenotype:		Abnormal vacuolar trafficking of soluble cargo proteins, and premature termination of the shoot apical meristem and of floral meristems. Plant missing both AGD5 and MTV1 are severely dwarfed, develop short siliques, exhibit abscission defect, and have altered subcellular distribution of clathrin-coated vesicle (CCV) cargo exported from the trans-Golgi network (TGN). {ECO:0000269\|PubMed:23771894}.
Sequence caution:		Sequence=AAB63649.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB01267.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};