PDBsum entry 2dbj

Transferase, signaling protein

PDB id: 2dbj

Contents

Protein chain

124 a.a. *

* Residue conservation analysis

PDB id:

2dbj

Name:

Transferase, signaling protein

Title:

Solution structures of the fn3 domain of human proto-oncogene tyrosine-protein kinase mer precursor

Structure:

Proto-oncogene tyrosine-protein kinase mer precursor. Chain: a. Fragment: fibronectin type iii domain. Synonym: c-mer, receptor tyrosine kinase mertk. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: mertk. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

M.Sato,N.Tochio,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

M.Sato et al. Solution structures of the fn3 domain of human proto-Oncogene tyrosine-Protein kinase mer precursor. To be published, .

Date:

15-Dec-05 Release date: 19-Dec-06

Protein chain

Q12866  (MERTK_HUMAN) -  Tyrosine-protein kinase Mer from Homo sapiens

Seq: 999 a.a.

Struc: 124 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site