PDBsum entry 2d9z

Signaling protein

PDB id: 2d9z

Contents

Protein chain

129 a.a. *

* Residue conservation analysis

PDB id:

2d9z

Name:

Signaling protein

Title:

Solution structure of the ph domain of protein kinasE C, nu type from human

Structure:

Protein kinasE C, nu type. Chain: a. Fragment: ph domain. Synonym: npkc-nu, protein kinase epk2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: prkcn, epk2. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

H.Li,T.Tomizawa,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

H.Li et al. Solution structure of the ph domain of protein kinase c, Nu type from human. To be published, .

Date:

13-Dec-05 Release date: 02-Jan-07

Protein chain

O94806  (KPCD3_HUMAN) -  Serine/threonine-protein kinase D3 from Homo sapiens

Seq: 890 a.a.

Struc: 129 a.a.*

* PDB and UniProt seqs differ at 11 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.11.13 - protein kinase C.
• Reaction:
  1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
  2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site