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UniProt functional annotation for O15034 | ||
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| UniProt code: O15034. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. {ECO:0000250}. |
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| Subunit: | |
Interacts with RIMS1, RIMS2, CACNA1D and CACNA1B, and potentially with other Ca(2+) channel alpha-1 isoforms. {ECO:0000250}. |
| Subcellular location: | |
Cell membrane {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Synaptic plasma membrane. {ECO:0000250}. |
| Domain: | |
The SH3 domains mediate binding to a proline-rich motif in RIMS1, RIMS2, CACNA1D and CACNA1B. {ECO:0000250}. |
| Similarity: | |
Belongs to the RIMBP family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAA20776.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.