| UniProt functional annotation for Q8N4X5 | |||
| UniProt code: Q8N4X5. |
| Organism: | Homo sapiens (Human). | |
| Taxonomy: | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. | |
| Function: | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. {ECO:0000269|PubMed:17412687}. | |
| Subunit: | Interacts with SRC. Interacts with LCK when tyrosine phosphorylated. {ECO:0000269|PubMed:17412687, ECO:0000269|PubMed:18844995}. | |
| Subcellular location: | Cytoplasm {ECO:0000269|PubMed:17412687}. | |
| Tissue specificity: | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. {ECO:0000269|PubMed:17412687}. | |
| Ptm: | Tyrosine phosphorylated (by SRC). {ECO:0000269|PubMed:17412687, ECO:0000269|PubMed:18844995}. | |
| Sequence caution: | Sequence=BAB67807.1; Type=Erroneous initiation; Evidence={ECO:0000305}; | |
Annotations taken from UniProtKB at the EBI.