PDBsum entry 2coe

Transferase

PDB id: 2coe

Contents

Protein chain

120 a.a. *

* Residue conservation analysis

PDB id:

2coe

Name:

Transferase

Title:

Solution structure of brct domain of terminal deoxynucleotidyltransferase

Structure:

Deoxynucleotidyltransferase, terminal variant. Chain: a. Fragment: brca1 c-turminus (brct) domain. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dntt, tdt. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

T.Nagashima et al. Solution structure of brct domain of terminal deoxynucleotidyltransferase. To be published, .

Date:

17-May-05 Release date: 17-Nov-05

Protein chain

P04053  (TDT_HUMAN) -  DNA nucleotidylexotransferase from Homo sapiens

Seq: 509 a.a.

Struc: 120 a.a.*

* PDB and UniProt seqs differ at 15 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.7.31 - Dna nucleotidylexotransferase.
• Reaction: DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site