UniProt functional annotation for P55040

UniProt code: P55040.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
 
Subunit: Interacts with calmodulin in a Ca(2+)-dependent manner. Binds ROCK1.
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue specificity: Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.
Induction: By mitogens.
Ptm: Phosphorylated on tyrosine residues.
Similarity: Belongs to the small GTPase superfamily. RGK family.

Annotations taken from UniProtKB at the EBI.