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PDBsum entry 2cab

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Hydro-lyase PDB id
2cab
Jmol
Contents
Protein chain
256 a.a.
Metals
_ZN

References listed in PDB file
Key reference
Title Structure, Refinement, And function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase i.
Authors K.K.Kannan, M.Ramanadham, T.A.Jones.
Ref. Ann N Y Acad Sci, 1984, 429, 49-60.
PubMed id 6430186
Abstract
The structure of human erythrocyte carbonic anhydrase I has been refined to a final R value of 19% to 2-A resolution by a combination of least squares refinement and model fitting in a three-dimensional graphics display. About 300 solvent atoms have been located bound to the protein molecule. An interesting hydrogen bond network involving Zn2+, the liganded solvent, side chain groups of Thr-199, Glu-106, Thr-7, and His-64 through two solvent molecules have been found that may be important for the catalytic mechanism of the carbonic anhydrase.
Secondary reference #1
Title Structure and function of carbonic anhydrases
Author K.K.Kannan.
Ref. biomolecular structure,, 1980, 1, 165.
Secondary reference #2
Title Crystal structure of carbonic anhydrase
Author K.K.Kannan.
Ref. biophysics and physiology ...
Secondary reference #3
Title Structure, Refinement, And function of human carbonic anhydrase-B
Authors K.K.Kannan, M.Ramanadham.
Ref. int.j.quantum chem.quantum, 1981, 20, 199.
Secondary reference #4
Title Structure and function of carbonic anhydrases. Imidazole binding to human carbonic anhydrase b and the mechanism of action of carbonic anhydrases.
Authors K.K.Kannan, M.Petef, K.Fridborg, H.Cid-Dresdner, S.Lövgren.
Ref. FEBS Lett, 1977, 73, 115-119.
PubMed id 402287
Abstract
Secondary reference #5
Title Crystal structure of human erythrocyte carbonic anhydrase b. Three-Dimensional structure at a nominal 2.2-A resolution.
Authors K.K.Kannan, B.Notstrand, K.Fridborg, S.Lövgren, A.Ohlsson, M.Petef.
Ref. Proc Natl Acad Sci U S A, 1975, 72, 51-55. [DOI no: 10.1073/pnas.72.1.51]
PubMed id 804171
Full text Abstract
Secondary reference #6
Title Structural relationship of human erythrocyte carbonic anhydrase isozymes b and c
Authors B.Notstrand, I.Vaara, K.K.Kannan.
Ref. isozymes-molecular structure, 1975, 1, 575.
PROCHECK
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 Headers