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PDBsum entry 2c6f

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Protein chain A    -    representing identical chain: B PDB id
2c6f
Protein chain A highlighted
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Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
3 sheets
2 beta hairpins
6 strands
31 helices
63 helix-helix interacs
39 beta turns
7 gamma turns
3 disulphides
Catalytic residues
E389-Y501
A332-E362-H331-H491-Y501
Active sites
AC1
AC2
AC3
AC5
AC7
AC8
BC1
BC2
BC3
CC2
CC4
Variants
Ala290Ser
Asp563Gly
Lys126Asn
Ala125Thr
Asp324Asn
Gly523Asp
Ala154Thr
Arg295Trp
Arg532Trp
Ser333Trp
Arg381Gln
Arg413His
Thr352Met
Ala232Ser
Pro456Arg
Asn131Ser
Tyr215Cys
Gly325Arg
Val268Met
PROSITE
ZINC_PROTEASE
  
Chain & (612 residues)

UniProt code: P12821 (ACE_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (1 domain) :
Domain Links CATH no.   Class Architecture
1 unassigned

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
Disulphides:   
    disulphide bond
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6  AC7  AC8  AC9  BC1
 BC2  BC3  BC4  BC5  BC6
 BC7  BC8  BC9  CC1  CC2
 CC3  CC4
PROSITE patterns:   
Low   High conservation


FASTA
file
Domain 1
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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