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UniProt functional annotation for Q59334 | ||
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| UniProt code: Q59334. |
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| Organism: | |
Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum). |
| Taxonomy: | |
Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum. |
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| Function: | |
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. |
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| Catalytic activity: | |
Reaction=2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen; Xref=Rhea:RHEA:24064, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:58126, ChEBI:CHEBI:356416; EC=4.2.1.24; |
| Activity regulation: | |
Stimulated by magnesium, inhibited by zinc. |
| Pathway: | |
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4. |
| Subunit: | |
Homooctamer. {ECO:0000269|PubMed:15327955, ECO:0000269|PubMed:16304458}. |
| Miscellaneous: | |
Does not seem to have a metal requirement for activity. {ECO:0000269|PubMed:15327955}. |
| Similarity: | |
Belongs to the ALAD family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.