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UniProt functional annotation for P07313 | ||
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| UniProt code: P07313. |
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| Organism: | |
Oryctolagus cuniculus (Rabbit). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus. |
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| Function: | |
Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain. {ECO:0000250}. |
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| Catalytic activity: | |
Reaction=ATP + L-seryl-[myosin light chain] = ADP + H(+) + O-phospho-L- seryl-[myosin light chain]; Xref=Rhea:RHEA:22004, Rhea:RHEA- COMP:13684, Rhea:RHEA-COMP:13685, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.18; |
| Catalytic activity: | |
Reaction=ATP + L-threonyl-[myosin light chain] = ADP + H(+) + O- phospho-L-threonyl-[myosin light chain]; Xref=Rhea:RHEA:53900, Rhea:RHEA-COMP:13686, Rhea:RHEA-COMP:13687, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.18; |
| Subunit: | |
May interact with centrin. {ECO:0000250}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:11733062}. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils. |
| Similarity: | |
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.