PDBsum entry 2aix

Membrane protein

PDB id: 2aix

Contents

Protein chain

258 a.a. *

Ligands

U1K

Waters ×234

* Residue conservation analysis

PDB id:

2aix

Name:

Membrane protein

Title:

X-ray structure of the glur2 ligand-binding core (s1s2j) in complex with (s)-thio-atpa at 2.2 a resolution.

Structure:

Glutamate receptor 2. Chain: a. Fragment: glur2-flop ligand-binding core (s1s2j).. Synonym: glur-2, glur-b, glur-k2, glutamate receptor ionotropic, ampa 2. Engineered: yes

Source:

Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: gria2, glur2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PDB file)

Resolution:

2.17Å R-factor: 0.198 R-free: 0.230

Authors:

J.S.Kastrup

Key ref:

M.M.Holm et al. Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-Ligand complex.. To be published, .

Date:

01-Aug-05 Release date: 09-Aug-05

Protein chain

P19491  (GRIA2_RAT) -  Glutamate receptor 2 from Rattus norvegicus

Seq: 883 a.a.

Struc: 258 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)