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PDBsum entry 2xdg

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protein ligands metals Protein-protein interface(s) links
Signaling protein PDB id
2xdg
Jmol
Contents
Protein chain
89 a.a. *
Ligands
EDO ×2
Metals
_MG ×3
Waters ×83
* Residue conservation analysis
PDB id:
2xdg
Name: Signaling protein
Title: Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.
Structure: Growth hormone-releasing hormone receptor. Chain: a, b. Fragment: extracellular domain, residues 34-123. Synonym: ghrh receptor, growth hormone-releasing factor grf receptor, grfr. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Resolution:
1.95Å     R-factor:   0.167     R-free:   0.222
Authors: A.C.W.Pike,A.Quigley,A.J.Barr,N.Burgess Brown,L.Shrestha,J.Y A.Chaikuad,M.Vollmar,J.R.C.Muniz,F.Von Delft,A.Edwards, C.H.Arrowsmith,J.Weigelt,C.Bountra,E.P.Carpenter
Key ref: A.C.W.Pike et al. Crystal structure of the extracellular domain of huma growth hormone releasing hormone receptor.. To be published, .
Date:
30-Apr-10     Release date:   16-Jun-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q02643  (GHRHR_HUMAN) -  Growth hormone-releasing hormone receptor
Seq:
Struc:
423 a.a.
89 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   1 term 
  Biological process     G-protein coupled receptor signaling pathway   1 term 
  Biochemical function     G-protein coupled receptor activity     1 term