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PDBsum entry 2px7

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protein Protein-protein interface(s) links
Transferase PDB id
2px7
Jmol
Contents
Protein chains
203 a.a. *
Waters ×160
* Residue conservation analysis
PDB id:
2px7
Name: Transferase
Title: Crystal structure of 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase from thermus thermophilus hb8
Structure: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase. Chain: a, b. Synonym: 4-diphosphocytidyl-2c-methyl-d-erythritol synthase, mep cytidylyltransferase, mct. Engineered: yes
Source: Thermus thermophilus hb8. Organism_taxid: 300852. Strain: hb8, dsm 579. Atcc: 27634. Gene: ispd, ttha0171. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.20Å     R-factor:   0.228     R-free:   0.248
Authors: L.Chen,M.Tsukuda,A.Ebihara,A.Shinkai,S.Kuramitsu,S.Yokoyama, L-Q.Chen,Z-J.Liu,D.Lee,S-H.Chang,D.Nguyen,J.P.Rose,B-C.Wang Southeast Collaboratory For Structural Genomics (Secsg), Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: L.Chen et al. Crystal structure of 2-C-Methyl-D-Erythritol 4-Phosphate cytidylyltransferase from thermus thermophilus hb8.. To be published, .
Date:
14-May-07     Release date:   12-Jun-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q5SLX2  (ISPD_THET8) -  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Seq:
Struc:
213 a.a.
203 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.60  - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
CTP
+ 2-C-methyl-D-erythritol 4-phosphate
= diphosphate
+ 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
      Cofactor: Manganese or magnesium
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     isoprenoid biosynthetic process   3 terms 
  Biochemical function     catalytic activity     4 terms