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PDBsum entry 2ppq

Go to PDB code: 
protein ligands metals links
Transferase PDB id
2ppq
Jmol
Contents
Protein chain
310 a.a. *
Ligands
PO4
Metals
_MG
Waters ×223
* Residue conservation analysis
PDB id:
2ppq
Name: Transferase
Title: Crystal structure of the homoserine kinase from agrobacteriu tumefaciens
Structure: Homoserine kinase. Chain: a. Synonym: hsk, hk. Engineered: yes
Source: Agrobacterium tumefaciens str.. Organism_taxid: 176299. Strain: c58. Atcc: 33970. Gene: thrb, atu0775, agr_c_1416. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Resolution:
2.00Å     R-factor:   0.190     R-free:   0.235
Authors: R.Zhang,X.Xu,H.Zheng,A.Savchenko,A.Edwards,A.Joachimiak,Midw Center For Structural Genomics (Mcsg)
Key ref: R.Zhang et al. The crystal structure of the homoserine kinase from agrobacterium tumefaciens.. To be published, .
Date:
30-Apr-07     Release date:   05-Jun-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8UHA8  (KHSE_AGRT5) -  Homoserine kinase
Seq:
Struc:
322 a.a.
310 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.1.39  - Homoserine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Threonine Biosynthesis
      Reaction: ATP + L-homoserine = ADP + O-phospho-L-homoserine
ATP
+ L-homoserine
= ADP
+
O-phospho-L-homoserine
Bound ligand (Het Group name = PO4)
matches with 41.67% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     phosphorylation   3 terms 
  Biochemical function     nucleotide binding     6 terms