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PDBsum entry 2o8y

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protein Protein-protein interface(s) links
Transferase PDB id
2o8y
Jmol
Contents
Protein chains
280 a.a. *
Waters ×59
* Residue conservation analysis
PDB id:
2o8y
Name: Transferase
Title: Apo irak4 kinase domain
Structure: Interleukin-1 receptor-associated kinase 4. Chain: a, b. Fragment: irak4 kinase domain. Synonym: irak-4, ny- ren-64 antigen. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: irak4. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Resolution:
2.40Å     R-factor:   0.244     R-free:   0.289
Authors: P.A.Boriack-Sjodin,C.Mol
Key ref: C.D.Mol et al. Crystal structures of the apo and inhibited irak4 kinase domain. To be published, .
Date:
12-Dec-06     Release date:   25-Dec-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9NWZ3  (IRAK4_HUMAN) -  Interleukin-1 receptor-associated kinase 4
Seq:
Struc:
460 a.a.
280 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.1  - Non-specific serine/threonine protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein phosphorylation   1 term 
  Biochemical function     transferase activity, transferring phosphorus-containing groups     3 terms