PDBsum entry 2nu1

Hydrolase

PDB id: 2nu1

Contents

Protein chains

185 a.a. *

51 a.a. *

Waters ×154

* Residue conservation analysis

PDB id:

2nu1

Name:

Hydrolase

Title:

Molecular structures of the complexes of sgpb with omtky3 aromatic p1 variants trp18i, his18i, phe18i and tyr18i

Structure:

Streptogrisin b. Chain: e. Fragment: residues 115-299. Synonym: protease b, sgpb, pronase enzyme b. Ovomucoid. Chain: i. Fragment: third domain, residues 135-185. Synonym: fragment. Engineered: yes.

Source:

Streptomyces griseus. Organism_taxid: 1911. Meleagris gallopavo. Turkey. Organism_taxid: 9103. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Dimer (from PQS)

Resolution:

1.80Å R-factor: 0.163

Authors:

K.S.Bateman,S.Anderson,W.Lu,M.A.Qasim,K.Huang,M.Laskowski Jr., M.N.G.James

Key ref:

K.S.Bateman et al. Molecular structures of the complexes of sgpb with omtky3 aromatic p1 variants trp18i, His18i, Phe18i and tyr18i. To be published, .

Date:

08-Nov-06 Release date: 21-Nov-06

Protein chain

P00777  (PRTB_STRGR) -  Streptogrisin-B from Streptomyces griseus

Seq: 299 a.a.

Struc: 185 a.a.

Protein chain

P68436  (IOVO_MELOE) -  Ovomucoid (Fragment) from Meleagris ocellata

Seq: 56 a.a.

Struc: 51 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: Chain E: E.C.3.4.21.81 - streptogrisin B.
• Reaction: Hydrolysis of proteins with specificity similar to trypsin.