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PDBsum entry 2loh

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protein Protein-protein interface(s) links
Neuropeptide PDB id
2loh
Jmol
Contents
Protein chains
43 a.a.
PDB id:
2loh
Name: Neuropeptide
Title: Dimeric structure of transmembrane domain of amyloid precurs in micellar environment
Structure: P3(42). Chain: a, b. Fragment: unp residues 686-726. Synonym: amyloid beta a4 protein. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: app, a4, ad1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
NMR struc: 12 models
Authors: K.Nadezhdin,E.Bocharov,O.Bocharova,A.Arseniev
Key ref: K.D.Nadezhdin et al. (2012). Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment. FEBS Lett, 586, 1687-1692. PubMed id: 22584060
Date:
24-Jan-12     Release date:   23-May-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P05067  (A4_HUMAN) -  Amyloid beta A4 protein
Seq:
Struc:
 
Seq:
Struc:
770 a.a.
43 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     integral to membrane   1 term 
  Biological process     nervous system development   1 term 

 

 
FEBS Lett 586:1687-1692 (2012)
PubMed id: 22584060  
 
 
Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment.
K.D.Nadezhdin, O.V.Bocharova, E.V.Bocharov, A.S.Arseniev.
 
  ABSTRACT  
 
No abstract given.