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PDBsum entry 2lgb

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protein Protein-protein interface(s) links
Hormone PDB id
2lgb
Jmol
Contents
Protein chains
22 a.a.
31 a.a.
PDB id:
2lgb
Name: Hormone
Title: Modified a22gly-b31arg human insulin
Structure: Insulin a chain. Chain: a. Engineered: yes. Insulin b chain. Chain: b. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ins. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc: 20 models
Authors: W.Bocian,L.Kozerski
Key ref: P.Borowicz et al. (2012). Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus. J Biomol NMR, 52, 365-370. PubMed id: 22350952
Date:
25-Jul-11     Release date:   11-Apr-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
22 a.a.
Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
31 a.a.
Key:    PfamA domain  Secondary structure

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biochemical function     hormone activity     1 term  

 

 
J Biomol NMR 52:365-370 (2012)
PubMed id: 22350952  
 
 
Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
P.Borowicz, E.Bednarek, W.Bocian, J.Sitkowski, B.Jaworska, J.Mikołajczyk, T.Głąbski, D.Stadnik, W.Surmacz, M.Bogiel, L.Kozerski.
 
  ABSTRACT  
 
No abstract given.