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PDBsum entry 2l7m

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protein links
Transcription PDB id
2l7m
Jmol
Contents
Protein chain
68 a.a.
PDB id:
2l7m
Name: Transcription
Title: Solution structure of the pitx2 homeodomain r24h mutant
Structure: Pituitary homeobox 2. Chain: p. Fragment: homeobox domain residues 85-144. Synonym: all1-responsive protein arp1 homeobox protein pit paired-like homeodomain transcription factor 2, rieg bicoid homeobox transcription factor, solurshin. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pitx2, arp1, rgs, rieg, rieg1. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc: 20 models
Authors: T.Doerdelmann,M.Rance,D.J.Kojetin,J.M.Baird-Titus
Key ref: T.Doerdelmann et al. Solution structure of the pitx2 homeodomain r24h muta. To be published, .
Date:
14-Dec-10     Release date:   14-Dec-11    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q99697  (PITX2_HUMAN) -  Pituitary homeobox 2
Seq:
Struc:
317 a.a.
68 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 9 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     regulation of transcription, DNA-dependent   1 term 
  Biochemical function     DNA binding     3 terms