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PDBsum entry 2l1r

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protein ligands metals Protein-protein interface(s) links
Metal binding protein PDB id
2l1r
Jmol
Contents
Protein chains
89 a.a. *
20 a.a. *
Ligands
SXK
Metals
_CA
* Residue conservation analysis
PDB id:
2l1r
Name: Metal binding protein
Title: The structure of the calcium-sensitizer, dfbp-o, in complex n-domain of troponin c and the switch region of troponin i
Structure: Troponin c. Chain: a. Fragment: n-terminal domain. Synonym: tn-c. Engineered: yes. Troponin i. Chain: b. Fragment: switch region. Synonym: cardiac troponin i.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnnc1, tnnc. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
NMR struc: 20 models
Authors: I.M.Robertson,Y.Sun,M.X.Li,B.D.Sykes
Key ref: I.M.Robertson et al. (2010). A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex. J Mol Cell Cardiol, 49, 1031-1041. PubMed id: 20801130 DOI: 10.1016/j.yjmcc.2010.08.019
Date:
03-Aug-10     Release date:   18-Aug-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P63316  (TNNC1_HUMAN) -  Troponin C, slow skeletal and cardiac muscles
Seq:
Struc:
161 a.a.
89 a.a.
Protein chain
Pfam   ArchSchema ?
P19429  (TNNI3_HUMAN) -  Troponin I, cardiac muscle
Seq:
Struc:
210 a.a.
20 a.a.
Key:    PfamA domain  Secondary structure

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     calcium ion binding     1 term  

 

 
DOI no: 10.1016/j.yjmcc.2010.08.019 J Mol Cell Cardiol 49:1031-1041 (2010)
PubMed id: 20801130  
 
 
A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex.
I.M.Robertson, Y.B.Sun, M.X.Li, B.D.Sykes.
 
  ABSTRACT  
 
No abstract given.