PDBsum entry 2hpz

Hydrolase

PDB id: 2hpz

Contents

Protein chains

279 a.a. *

11 a.a. *

Ligands

NO3 ×2

Metals

_CA

Waters ×338

* Residue conservation analysis

PDB id:

2hpz

Name:

Hydrolase

Title:

Crystal structure of proteinase k complex with a synthetic peptide klkllvvirlk at 1.69 a resolution

Structure:

Proteinase k. Chain: a. Synonym: tritirachium alkaline proteinase, endopeptidase k. 11-mer synthetic peptide. Chain: b. Engineered: yes

Source:

Engyodontium album. Organism_taxid: 37998. Synthetic: yes. Other_details: chemically synthesized

Biol. unit:

Dimer (from PQS)

Resolution:

1.69Å R-factor: 0.160 R-free: 0.179

Authors:

R.Prem Kumar,A.K.Singh,R.K.Somvanshi,N.Singh,S.Sharma,P.Kaur,S.Dey, A.Bhushan,T.P.Singh

Key ref:

R.Prem kumar et al. Crystal structure of proteinase k complex with a synthetic peptide klkllvvirlk at 1.69 a resolution. To be published, .

Date:

18-Jul-06 Release date: 01-Aug-06

Protein chain

A0A0H2URJ7  (A0A0H2URJ7_STRPN) -  Sugar ABC transporter, sugar-binding protein from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

Seq: 419 a.a.

Struc: 279 a.a.*

Protein chain

No UniProt id for this chain

Struc: 11 a.a.

* PDB and UniProt seqs differ at 252 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.