spacer
spacer

PDBsum entry 2grj

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Transferase PDB id
2grj
Jmol
Contents
Protein chains
(+ 2 more) 179 a.a. *
Ligands
ADP ×8
COD ×8
Metals
_CL ×4
Waters ×67
* Residue conservation analysis
PDB id:
2grj
Name: Transferase
Title: Crystal structure of dephospho-coa kinase (ec 2.7.1.24) (dephosphocoenzyme a kinase) (tm1387) from thermotoga marit 2.60 a resolution
Structure: Dephospho-coa kinase. Chain: a, b, c, d, e, f, g, h. Synonym: dephosphocoenzyme a kinase. Engineered: yes
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: coae. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.60Å     R-factor:   0.193     R-free:   0.245
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref: Joint center for structural genomics (jcsg) Crystal structure of dephospho-Coa kinase (EC 2.7.1.24) (dephosphocoenzyme a kinase) (tm1387) from thermotoga maritima at 2.60 a resolution. To be published, .
Date:
24-Apr-06     Release date:   23-May-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9X1A7  (COAE_THEMA) -  Dephospho-CoA kinase
Seq:
Struc:
180 a.a.
179 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.1.24  - Dephospho-CoA kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Coenzyme A Biosynthesis (late stages)
      Reaction: ATP + 3'-dephospho-CoA = ADP + CoA
ATP
+ 3'-dephospho-CoA
=
ADP
Bound ligand (Het Group name = ADP)
corresponds exactly
+
CoA
Bound ligand (Het Group name = COD)
matches with 91.67% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     phosphorylation   2 terms 
  Biochemical function     nucleotide binding     5 terms