PDBsum entry 2duj

Hydrolase

PDB id: 2duj

Contents

Protein chain

279 a.a. *

Ligands

LEU-LEU-PHE-ASN-ASP

NO3

Metals

_CA

Waters ×303

* Residue conservation analysis

PDB id:

2duj

Name:

Hydrolase

Title:

Crystal structure of the complex formed between proteinase k and a synthetic peptide leu-leu-phe-asn-asp at 1.67 a resolution

Structure:

Proteinase k. Chain: a. Synonym: tritirachium alkaline proteinase, endopeptidase k. Llfnd. Chain: p. Engineered: yes

Source:

Engyodontium album. Organism_taxid: 37998. Synthetic: yes. Other_details: lactoferrin peptide, chemically synthesized

Biol. unit:

Dimer (from PQS)

Resolution:

1.67Å R-factor: 0.164 R-free: 0.192

Authors:

A.K.Singh,N.Singh,R.K.Somvanshi,D.Gupta,S.Sharma,T.P.Singh

Key ref:

A.K.Singh et al. Crystal structure of the complex of proteinase k with a specific lactoferrin peptide val-Leu-Leu-His at 1.93 a resolution. To be published, .

Date:

23-Jul-06 Release date: 08-Aug-06

Protein chain

P06873  (PRTK_PARAQ) -  Proteinase K from Parengyodontium album

Seq: 384 a.a.

Struc: 279 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.