PDBsum entry 2dqk

Hydrolase

PDB id: 2dqk

Contents

Protein chain

279 a.a. *

Ligands

VAL-LEU-LEU-HIS

NO3

Metals

_CA

Waters ×291

* Residue conservation analysis

PDB id:

2dqk

Name:

Hydrolase

Title:

Crystal structure of the complex of proteinase k with a specific lactoferrin peptide val-leu-leu-his at 1.93 a resolution

Structure:

Proteinase k. Chain: a. Synonym: tritirachium alkaline proteinase, endopeptidase k. Vllh. Chain: p. Engineered: yes

Source:

Engyodontium album. Organism_taxid: 37998. Strain: limber. Synthetic: yes. Other_details: lactoferrin peptide, chemically synthesized

Biol. unit:

Dimer (from PQS)

Resolution:

1.93Å R-factor: 0.154 R-free: 0.187

Authors:

A.K.Singh,N.Singh,S.Sharma,S.Dey,A.Bhushan,T.P.Singh

Key ref:

A.K.Singh et al. Crystal structure of the complex of proteinase k with a specific lactoferrin peptide val-Leu-Leu-His at 1.93 resolution. To be published, .

Date:

29-May-06 Release date: 20-Jun-06

Protein chain

P06873  (PRTK_PARAQ) -  Proteinase K from Parengyodontium album

Seq: 384 a.a.

Struc: 279 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.