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PDBsum entry 2bmw

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protein ligands links
Oxidoreductase PDB id
2bmw
Jmol
Contents
Protein chain
295 a.a. *
Ligands
FAD
SO4
Waters ×586
* Residue conservation analysis
PDB id:
2bmw
Name: Oxidoreductase
Title: Ferredoxin: NADP+reductase mutant with thr 155 replaced by gly, ala 160 replaced by thr, leu 263 replaced by pro, arg 264 replaced by pro and gly 265 replaced by pro (t155g- a160t-l263p-r264p-g265p)
Structure: Ferredoxin--NADP reductase. Chain: a. Fragment: residues 137-440. Synonym: ferredoxin-NADP+ reductase, fnr. Engineered: yes. Mutation: yes. Other_details: mutations t155g, a160t, l263p, r264p and g265p
Source: Anabaena sp.. Cyanobacteria. Organism_taxid: 1168. Strain: pcc 7119. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.5Å     R-factor:   0.185     R-free:   0.207
Authors: M.Martinez-Julvez,J.A.Hermoso,I.Perez-Dorado,M.Medina, J.Tejero,C.Gomez-Moreno
Key ref: M.Martinez-Julvez et al. Determinant regions of ferredoxin-Nadp(h) reductase in coenzyme specificity. To be published, .
Date:
16-Mar-05     Release date:   22-Jun-06    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P21890  (FENR_ANASO) -  Ferredoxin--NADP reductase
Seq:
Struc:
440 a.a.
295 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 6 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.1.18.1.2  - Ferredoxin--NADP(+) reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Methionine Synthase
      Reaction: 2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH
2 × reduced ferredoxin
+ NADP(+)
+ H(+)
= 2 × oxidized ferredoxin
+ NADPH
      Cofactor: FAD
FAD
Bound ligand (Het Group name = FAD) corresponds exactly
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   1 term 
  Biochemical function     oxidoreductase activity     1 term