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PDBsum entry 2ap9

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protein metals Protein-protein interface(s) links
Signaling protein,transferase PDB id
2ap9
Jmol
Contents
Protein chains
(+ 0 more) 299 a.a. *
Metals
_NI
_MG ×2
Waters ×113
* Residue conservation analysis
PDB id:
2ap9
Name: Signaling protein,transferase
Title: Crystal structure of acetylglutamate kinase from mycobacteri tuberculosis cdc1551
Structure: Acetylglutamate kinase. Chain: a, b, c, d, e, f. Fragment: acetylglutamate kinase. Synonym: NAG kinase. Agk. N-acetyl-l-glutamate 5-phosphotra engineered: yes. Mutation: yes
Source: Mycobacterium tuberculosis. Organism_taxid: 83331. Strain: cdc1551. Gene: argb, rv1654, mt1692. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Hexamer (from PQS)
Resolution:
2.80Å     R-factor:   0.258     R-free:   0.284
Authors: K.R.Rajashankar,R.Kniewel,K.Lee,C.D.Lima,S.K.Burley,New York Research Center For Structural Genomics (Nysgxrc)
Key ref: K.R.Rajashankar et al. Crystal structure of acetylglutamate kinase from mycobacterium tuberculosis cdc1551. To be published, .
Date:
15-Aug-05     Release date:   30-Aug-05    
PROCHECK
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 Headers
 References

Protein chains
Pfam  
P9WQ01  (ARGB_MYCTU) -  Acetylglutamate kinase
Seq:
Struc:
294 a.a.
299 a.a.*
Key:    Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.7.2.8  - Acetylglutamate kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Ornithine Biosynthesis
      Reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate
ATP
+ N-acetyl-L-glutamate
= ADP
+ N-acetyl-L-glutamate 5-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     phosphorylation   3 terms 
  Biochemical function     nucleotide binding     5 terms