spacer
spacer

PDBsum entry 2abi

Go to PDB code: 
protein ligands links
Transcription regulator PDB id
2abi
Jmol
Contents
Protein chains
230 a.a. *
Ligands
1CA ×3
Waters ×381
* Residue conservation analysis
PDB id:
2abi
Name: Transcription regulator
Title: Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
Structure: Mineralocorticoid receptor. Chain: a, b, c. Fragment: ligand-binding domain. Synonym: mr. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: uv20hl21-27. Gene: nr3c2, mcr, mlr. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.33Å     R-factor:   0.207     R-free:   0.264
Authors: J.Huyet,G.-M.Pinon,M.Rochel,C.Mayer,M.-E.Rafestin-Oblin, J.Fagart
Key ref: J.Huyet et al. Crystal structure of the human mineralocorticoid receptor ligand-Binding domain bound to deoxycorticosterone. To be published, .
Date:
15-Jul-05     Release date:   25-Jul-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P08235  (MCR_HUMAN) -  Mineralocorticoid receptor
Seq:
Struc:
 
Seq:
Struc:
984 a.a.
230 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     steroid hormone mediated signaling pathway   2 terms 
  Biochemical function     DNA binding     3 terms