UniProt functional annotation for P24327

UniProt code: P24327.

Organism: Bacillus subtilis (strain 168).
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
 
Function: Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo. {ECO:0000269|PubMed:12634326}.
 
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Domain: All three domains (PPIase domain and the flanking N- and C-terminal domains) are essential for activity.
Similarity: Belongs to the PrsA family. {ECO:0000305}.
Similarity: Contains 1 PpiC domain. {ECO:0000305}.
Sequence caution: Sequence=AAA22825.1; Type=Miscellaneous discrepancy; Note=Sequencing errors. The N-terminus of this sequence is probably the N-terminus of phrI.; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.