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PDBsum entry 1z6u
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Contents |
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* Residue conservation analysis
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PDB id:
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Ligase
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Title:
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Np95-like ring finger protein isoform b [homo sapiens]
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Structure:
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Np95-like ring finger protein isoform b. Chain: a, b. Fragment: ring zinc finger, residues 672-802. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Biol. unit:
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Dimer (from
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Resolution:
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2.10Å
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R-factor:
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0.225
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R-free:
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0.283
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Authors:
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J.R.Walker,G.V.Avvakumov,S.Xue,E.M.Newman,F.Mackenzie,M.Sundstrom, C.Arrowsmith,A.Edwards,A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
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Key ref:
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J.R.Walker
et al.
2.1 angstrom crystal structure of the human ubiquitin liagse nirf.
To be published,
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Date:
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23-Mar-05
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Release date:
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03-May-05
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PROCHECK
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Headers
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References
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Q96PU4
(UHRF2_HUMAN) -
E3 ubiquitin-protein ligase UHRF2 from Homo sapiens
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Seq:
Struc:
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802 a.a.
115 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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Links
