UniProt functional annotation for P33307

UniProt code: P33307.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Export receptor for importin alpha (SRP1). Mediates importin- alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm. {ECO:0000269|PubMed:10394916, ECO:0000269|PubMed:9744791, ECO:0000269|PubMed:9774694, ECO:0000269|PubMed:9857050}.
 
Subunit: Binds with high affinity to SRP1 only in the presence of RanGTP. The complex is dissociated by the RanGTP-binding protein YRB1. {ECO:0000269|PubMed:15602554}.
Subcellular location: Cytoplasm. Nucleus.
Miscellaneous: Present with 23500 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the XPO2/CSE1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.