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PDBsum entry 1ymc
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Oxygen transport
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PDB id
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1ymc
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References listed in PDB file
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Key reference
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Title
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Three-Dimensional structure of cyanomet-Sulfmyoglobin c.
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Authors
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S.V.Evans,
B.P.Sishta,
A.G.Mauk,
G.D.Brayer.
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Ref.
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Proc Natl Acad Sci U S A, 1994,
91,
4723-4726.
[DOI no: ]
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PubMed id
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Note In the PDB file this reference is
annotated as "TO BE PUBLISHED".
The citation details given above were identified by an automated
search of PubMed on title and author
names, giving a
perfect match.
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Abstract
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The atomic structure of horse heart cyanomet-sulfmyoglobin C has been
established by x-ray crystallographic techniques to a resolution of 2.0 A with
an R value of 0.129. The protoheme IX prosthetic group of this thermodynamically
stable sulfmyoglobin derivative has been converted to a chlorin in which the
pyrrole ring bearing the 4-vinyl group is saturated and possesses an exocyclic
thiolene ring. This study provides the three-dimensional structure of a protein
with an iron-chlorin prosthetic group. The overall conformation of the
surrounding polypeptide chain of the modified protein is very similar to that of
the native protein. However, the addition of the sulfur atom has caused a
distortion of the prosthetic group from that in the native protein to result in
the repositioning of the side chains of some residues in the heme pocket.
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Secondary reference #1
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Title
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High-Resolution study of the three-Dimensional structure of horse heart metmyoglobin.
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Authors
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S.V.Evans,
G.D.Brayer.
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Ref.
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J Mol Biol, 1990,
213,
885-897.
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PubMed id
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Secondary reference #2
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Title
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Horse heart metmyoglobin. A 2.8-A resolution three-Dimensional structure determination.
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Authors
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S.V.Evans,
G.D.Brayer.
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Ref.
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J Biol Chem, 1988,
263,
4263-4268.
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PubMed id
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Secondary reference #3
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Title
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Crystallization and preliminary diffraction data for horse heart metmyoglobin.
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Authors
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C.Sherwood,
A.G.Mauk,
G.D.Brayer.
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Ref.
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J Mol Biol, 1987,
193,
227.
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PubMed id
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