UniProt functional annotation for P28161

UniProt code: P28161.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:16549767}.
 
Catalytic activity: RX + glutathione = HX + R-S-glutathione. {ECO:0000269|PubMed:16549767}.
Subunit: Homodimer. {ECO:0000269|PubMed:16549767, ECO:0000269|PubMed:19808963, ECO:0000269|PubMed:8182750}.
Subcellular location: Cytoplasm.
Tissue specificity: Muscle.
Similarity: Belongs to the GST superfamily. Mu family. {ECO:0000305}.
Similarity: Contains 1 GST C-terminal domain. {ECO:0000305}.
Similarity: Contains 1 GST N-terminal domain. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.