UniProt functional annotation for Q9H2H8

UniProt code: Q9H2H8.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Subunit: Identified in the spliceosome C complex. {ECO:0000269|PubMed:11991638}.
Tissue specificity: Ubiquitous. Detected at low levels. {ECO:0000269|PubMed:11435694}.
Similarity: Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily. {ECO:0000305}.
Similarity: Contains 1 PPIase cyclophilin-type domain. {ECO:0000255|PROSITE-ProRule:PRU00156}.

Annotations taken from UniProtKB at the EBI.