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PDBsum entry 1xuo
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Immune system
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PDB id
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1xuo
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References listed in PDB file
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Key reference
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Title
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1,4-Diazepane-2,5-Diones as novel inhibitors of lfa-1.
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Authors
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S.Wattanasin,
J.Kallen,
S.Myers,
Q.Guo,
M.Sabio,
C.Ehrhardt,
R.Albert,
U.Hommel,
G.Weckbecker,
K.Welzenbach,
G.Weitz-Schmidt.
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Ref.
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Bioorg Med Chem Lett, 2005,
15,
1217-1220.
[DOI no: ]
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PubMed id
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Abstract
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1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1
inhibitors. The synthesis, structure, and biological evaluation of these
1,4-diazepine-2,5-diones and related derivatives are described.
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