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PDBsum entry 1xcw

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Protein chain A PDB id
1xcw
Protein chain A highlighted
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Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
8 sheets
5 beta alpha beta units
6 beta hairpins
3 beta bulges
24 strands
22 helices
11 helix-helix interacs
48 beta turns
5 gamma turns
5 disulphides
Catalytic residues
D197-D300-E233
D197-E233
D197-D236
Variants
Thr84Asn
  
Chain (496 residues)

UniProt code: P04746 (AMYP_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (2 domains) :
Domain Links CATH no.   Class Architecture
1 3.20.20.80 = Alpha Beta Alpha-Beta Barrel
2 2.60.40.1180 = Mainly Beta Sandwich

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
Disulphides:   
    disulphide bond
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4

Jmol
RasMol

FASTA
file
Domain 1
Topology diagram


Hera


Domain 2
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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