PDBsum entry 1x5l

Signaling protein

PDB id: 1x5l

Contents

Protein chain

111 a.a. *

* Residue conservation analysis

PDB id:

1x5l

Name:

Signaling protein

Title:

Solution structure of the second fn3 domain of eph receptor a8 protein

Structure:

Ephrin type-a receptor 8. Chain: a. Fragment: fn3 domain. Synonym: tyrosine-protein kinase receptor eek, eph-and elk-related kinase, hek3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh16961. Other_details: cell free protein synthesis

NMR struc:

20 models

Authors:

X.R.Qin,T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

X.R.Qin et al. Solution structure of the second fn3 domain of eph receptor a8 protein. To be published, .

Date:

16-May-05 Release date: 16-Nov-05

Protein chain

P29322  (EPHA8_HUMAN) -  Ephrin type-A receptor 8 from Homo sapiens

Seq: 1005 a.a.

Struc: 111 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site