PDBsum entry 1x2p

Transferase

PDB id: 1x2p

Contents

Protein chain

68 a.a. *

* Residue conservation analysis

PDB id:

1x2p

Name:

Transferase

Title:

Solution structure of the sh3 domain of the protein arginine n- methyltransferase 2

Structure:

Protein arginine n-methyltransferase 2. Chain: a. Fragment: sh3 domain. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hrmt1l1. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

E.Chikayama,T.Kigawa,K.Saito,S.Koshiba,M.Inoue,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

E.Chikayama et al. Solution structure of the sh3 domain of the protein arginine n-Methyltransferase 2. To be published, .

Date:

26-Apr-05 Release date: 26-Oct-05

Protein chain

P55345  (ANM2_HUMAN) -  Protein arginine N-methyltransferase 2 from Homo sapiens

Seq: 433 a.a.

Struc: 68 a.a.*

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.1.1.319 - type I protein arginine methyltransferase.
• Reaction: L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)- dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site