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UniProt functional annotation for P20165 | ||
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| UniProt code: P20165. |
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| Organism: | |
Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Protobothrops. |
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| Function: | |
Major venom non-hemorrhagic metalloproteinase. |
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| Catalytic activity: | |
Reaction=Cleavage of 3-Asn-|-Gln-4, 10-His-|-Leu-11 and 14-Ala-|-Leu-15 in the insulin B chain, and the bond Z-Gly-Pro-|-Leu-Gly-Pro in a small molecule substrate of microbial collagenase.; EC=3.4.24.53; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250}; |
| Subunit: | |
Monomer. {ECO:0000250}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Expressed by the venom gland. |
| Similarity: | |
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.