UniProt functional annotation for Q9SXZ2



	UniProt functional annotation for Q9SXZ2

UniProt code: Q9SXZ2.

Organism: Arabidopsis thaliana (Mouse-ear cress).

Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.

Function: Component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. Translated in leaves and then transported to the shoot apical meristem where it activates the transcription of several floral meristem identity genes. May play a role in both the autonomous and the long-day flowering pathways. {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:16099980, ECO:0000269|PubMed:16155177}.

Subunit: Interacts with FD/BZIP14 and FDP/BZIP27 (PubMed:16099979, PubMed:16099980). Interacts with FTIP1 in phloem companion cells (PubMed:22529749). Interacts with NAKR1 (PubMed:27255839). {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:16099980, ECO:0000269|PubMed:22529749, ECO:0000269|PubMed:27255839}.

Subcellular location: Cytoplasm {ECO:0000269|PubMed:16099979}. Nucleus {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:22529749}. Endoplasmic reticulum {ECO:0000269|PubMed:22529749}.

Tissue specificity: Mostly localized in leaves vasculature. {ECO:0000269|PubMed:15618421}.

Developmental stage: Expression gradually increases with time under both long-day (LD) and short-day (SD) photoperiods. Under LD conditions, expression is first detected on day 4 and plateaued around day 6, preceeding floral commitment around days 9 and 10.

Induction: Levels follow a circadian cycle with a progressive accumulation during the day time (PubMed:25343985). By light. Expression is delayed and reduced under SD conditions. Repressed by FLC. Up-Regulated by VOZ1 and/or VOZ2 (PubMed:22904146). Up-regulated by APL/FE (PubMed:26239308). Down-regulated by the H3K36me2 modification at the FT locus produced by the interaction between EFM and JMJ30 (PubMed:25132385). Repressed by MYB56 (PubMed:25343985). {ECO:0000269|PubMed:16099980, ECO:0000269|PubMed:22904146, ECO:0000269|PubMed:25132385, ECO:0000269|PubMed:25343985, ECO:0000269|PubMed:26239308}.

Miscellaneous: Mutagenesis of Tyr-85 to His converts the activator of flowering 'FLOWERING LOCUS T' into a 'TERMINAL FLOWER 1'-like repressor of flowering.

Similarity: Belongs to the phosphatidylethanolamine-binding protein family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Arabidopsis thaliana (Mouse-ear cress).
Taxonomy:		Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.



Function:		Component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. Translated in leaves and then transported to the shoot apical meristem where it activates the transcription of several floral meristem identity genes. May play a role in both the autonomous and the long-day flowering pathways. {ECO:0000269\|PubMed:16099979, ECO:0000269\|PubMed:16099980, ECO:0000269\|PubMed:16155177}.


Subunit:		Interacts with FD/BZIP14 and FDP/BZIP27 (PubMed:16099979, PubMed:16099980). Interacts with FTIP1 in phloem companion cells (PubMed:22529749). Interacts with NAKR1 (PubMed:27255839). {ECO:0000269\|PubMed:16099979, ECO:0000269\|PubMed:16099980, ECO:0000269\|PubMed:22529749, ECO:0000269\|PubMed:27255839}.
Subcellular location:		Cytoplasm {ECO:0000269\|PubMed:16099979}. Nucleus {ECO:0000269\|PubMed:16099979, ECO:0000269\|PubMed:22529749}. Endoplasmic reticulum {ECO:0000269\|PubMed:22529749}.
Tissue specificity:		Mostly localized in leaves vasculature. {ECO:0000269\|PubMed:15618421}.
Developmental stage:		Expression gradually increases with time under both long-day (LD) and short-day (SD) photoperiods. Under LD conditions, expression is first detected on day 4 and plateaued around day 6, preceeding floral commitment around days 9 and 10.
Induction:		Levels follow a circadian cycle with a progressive accumulation during the day time (PubMed:25343985). By light. Expression is delayed and reduced under SD conditions. Repressed by FLC. Up-Regulated by VOZ1 and/or VOZ2 (PubMed:22904146). Up-regulated by APL/FE (PubMed:26239308). Down-regulated by the H3K36me2 modification at the FT locus produced by the interaction between EFM and JMJ30 (PubMed:25132385). Repressed by MYB56 (PubMed:25343985). {ECO:0000269\|PubMed:16099980, ECO:0000269\|PubMed:22904146, ECO:0000269\|PubMed:25132385, ECO:0000269\|PubMed:25343985, ECO:0000269\|PubMed:26239308}.
Miscellaneous:		Mutagenesis of Tyr-85 to His converts the activator of flowering 'FLOWERING LOCUS T' into a 'TERMINAL FLOWER 1'-like repressor of flowering.
Similarity:		Belongs to the phosphatidylethanolamine-binding protein family. {ECO:0000305}.