| UniProt functional annotation for P31334 | |||
| UniProt code: P31334. |
| Organism: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Taxonomy: | Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. | |
| Function: | Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. {ECO:0000305|PubMed:24675956, ECO:0000305|PubMed:25609543}. | |
| Subunit: | Component of the mitochondrial large ribosomal subunit (mt- LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins. {ECO:0000269|PubMed:24675956, ECO:0000269|PubMed:3060376}. | |
| Subcellular location: | Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}. | |
| Miscellaneous: | Present with 3200 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. | |
| Similarity: | Belongs to the universal ribosomal protein uL3 family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.