|
|
||
|
|
|
|
|
UniProt functional annotation for Q9K8V3 | ||
|
|
|
|
|
|
||
| UniProt code: Q9K8V3. |
|
||
| Organism: | |
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus. |
|
||
|
||
| Function: | |
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. {ECO:0000250}. |
|
||
| Catalytic activity: | |
Reaction=L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N- acetyl-L-glutamate; Xref=Rhea:RHEA:15349, ChEBI:CHEBI:29985, ChEBI:CHEBI:44337, ChEBI:CHEBI:46911, ChEBI:CHEBI:57805; EC=2.3.1.35; |
| Catalytic activity: | |
Reaction=acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate; Xref=Rhea:RHEA:24292, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:44337, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.1; |
| Activity regulation: | |
Feedback inhibition by L-ornithine. {ECO:0000250}. |
| Pathway: | |
Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. |
| Pathway: | |
Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl- L-ornithine from L-glutamate: step 1/4. |
| Subunit: | |
Heterotetramer of two alpha and two beta chains. {ECO:0000269|Ref.2}. |
| Subcellular location: | |
Cytoplasm {ECO:0000305}. |
| Miscellaneous: | |
Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway. |
| Similarity: | |
Belongs to the ArgJ family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.